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Should men with symptoms of low testosterone but without hypogonadism be prescribed testosterone therapy?

Testosterone replacement also affects metabolic parameters, with effects on cholesterol occurring in 4 weeks, peaking at 6–12 months, and blood sugar levels improving after 3–12 months. On average, it takes about 3 weeks to see an improvement in sexual desire (libido), energy, and mood. Men are increasingly seeking testosterone measurement for a variety of reasons and GPs are thus faced with a burgeoning number of ‘low testosterone’ results needing to be actioned. As the diagnosis of hypogonadism is not always straightforward, careful clinical and biochemical assessment is essential prior to prescribing. A doctor can check your testosterone level with a simple blood test.

An experienced urologist can help identify if Low T is the cause of your symptoms and provide effective treatment options, including testosterone replacement therapy (TRT). Low testosterone, otherwise known as ‘Low T,’ is a common condition that affects nearly 40 percent of men over the age of 45. Testosterone is the hormone that helps men maintain and develop muscle mass, red blood cell levels, bone density, sexual and reproductive function and a general sense of well-being. While levels start dropping at around age 30, when they get too low, men can start to notice some unpleasant symptoms.

It is well known that exogenous testosterone can – and often will – cause infertility. Unfortunately, some doctors prescribe testosterone to treat infertility, and inadvertently make the problem worse. The hormone seeps through the skin, and is slowly released into the blood.

However, if you have damaged (most commonly related to prior chemotherapy) or missing testicles, they can’t respond to the increased levels of gonadotropins. As a result, your testicles make too little or no testosterone and sperm. Every so often I have a patient who cannot get total testosterone levels above 300 ng/dL despite maximal therapy (e.g. HCG 4,000 IU three times a week combined with anastrazole 1 mg daily). In this situation, the Leydig cells that produce testosterone within the testicles are presumably not functioning properly and do not respond to LH stimulation. There have been some case reports of men who have developed antibodies against HCG, making it less effective.

Without enough sperm, they may not be able to father a child. People assigned male at birth and people assigned female at birth produce testosterone, but this article focuses on symptoms of low testosterone in people assigned male at birth. A primary care physician may refer an individual to a urologist, who specializes in diseases of the male reproductive system, or to an endocrinologist who specializes in hormone-related diseases. When the cells are full of glucose, the body stores the excess in fat cells, which may lead to conditions such as type 2 diabetes and obesity. For example, a bone density test can show diminished bone mass, one result of low testosterone. To diagnose low testosterone, a doctor will often perform a physical evaluation and review the person’s symptoms. The doctor may also request testing to look for additional signs.

Whichever delivery method you choose, these treatments can stop the symptoms of low T and get your life back on track. Exogenous testosterone may suppress spermatogenesis and men desiring fertility should thus be referred to local reproductive services before starting. Often, we find that anxiety or depression – not hormonal imbalances – are the root cause of low-T-like symptoms. Suppressing your emotions can interfere with normal functions, such as focusing at work or maintaining an erection. If you truly have low-T, underlying stressors can make symptoms worse.

Some doctors may prescribe testosterone off-label to females to improve libido, but this use has not been approved by the Food and Drug Administration (FDA). Most cases of low testosterone are treatable, and being aware of the symptoms can help a person receive an early diagnosis and treatment. In people with fertility problems, low testosterone may be a symptom of a testicular function issue causing infertility rather than a cause of infertility itself. A reduction in testosterone can lead to an does sprinting increase testosterone in body fat.

TRT is also available as injections, skin patches, and pellets placed under the skin. Most people will notice relief from symptoms within 3–60 weeks of starting TRT. People with low testosterone may find it difficult to fall or stay asleep. Semen is the fluid that makes up the majority of male ejaculate. This article will use the terms “male,” “female,” or both to refer to sex assigned at birth.

This is referred to as hypogonadism, testosterone deficiency syndrome (TD), low testosterone (Low-T), or andropause. While each of the symptoms above may result from lowered testosterone levels, they may also be normal side effects of aging. Most men feel improvement in symptoms within four to six weeks of taking testosterone replacement therapy, although changes like increases in muscle mass may take from three to six months.

The method of administration will depend on the individual’s health profile and lifestyle, as well as the preference and guidance of the healthcare provider. Regular monitoring by a healthcare professional is essential to adjust dosages and ensure the therapy’s effectiveness while minimising side effects. If you suspect you’re dealing with such symptoms, the team at Arlington Family Practice in Arlington, Massachusetts, can test your testosterone levels and treat your symptoms. Read on to learn some of the common symptoms of low testosterone, which can improve significantly with proper treatment. It is important to distinguish between a normal decline of testosterone levels and hypogonadism. There have been concerns about testosterone therapy and cardiovascular events, like strokes, blood clots, and heart disease. However, it is not definitely known whether TRT raises or lowers risk of cardiovascular problems.